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|Turkey Tail grown in sawdust|
Turkey tail is renowned in Asia as a source for cancer therapy. The Japanese company Kureha first screened many polypore mushrooms and found that turkey tails produced a profound immune response, a discovery confirmed by many other subsequent studies. The Kureha researchers received a patent for extracting both the mycelium and mushrooms in 1976 and derivative U.S. patents through 1981 (long since expired). http://toughertimes.blogspot.com/2015/05/paul-stamets-john-b-wells-mushrooms.html
The extraction method led to marketing "PSK" (polysaccharide Krestin®) and later "PSP," both protein-bound polysaccharides. PSK became recognized as a cancer drug in Japan and approved under somewhat controversial conditions. Before approving a foreign-made drug, the United States Food and Drug Administration (FDA) has many requirements. One is that the Active Principal Ingredient (API) needs to be disclosed. Therein lies the problem. PSK is an assortment of sugars and attached proteins but has no unique molecule responsible for its impact on the immune system. Without that API, verification from batch-to-batch is not possible. Thus, it is classified as an undefined drug. This is one reason why PSK cannot be legally imported nor marketed in the United States.
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